Differential effects of viroporin inhibitors against feline infectious peritonitis virus serotypes I and II
نویسندگان
چکیده
منابع مشابه
Adverse effects of feline IL-12 during DNA vaccination against feline infectious peritonitis virus.
Cell-mediated immunity is thought to play a decisive role in protecting cats against feline infectious peritonitis (FIP), a progressive and lethal coronavirus disease. In view of the potential of DNA vaccines to induce cell-mediated responses, their efficacy to induce protective immunity in cats was evaluated. The membrane (M) and nucleocapsid (N) proteins were chosen as antigens, because antib...
متن کاملPrevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis.
Feline coronaviruses (FCoV) vary widely in virulence causing a spectrum of clinical manifestations reaching from subclinical course to fatal feline infectious peritonitis (FIP). Independent of virulence variations they are separated into two different types, type I, the original FCoV, and type II, which is closely related to canine coronavirus (CCV). The prevalence of FCoV types in Austrian cat...
متن کاملUnderstanding Feline Infectious Peritonitis
Dr. Niels C. Pedersen is Director of the Veterinary Genetics Laboratory and Director of the Center for Companion Animal Health at the University of California at Davis. Dr. Pedersen is an international authority on infectious diseases and immunological disorders in small animals and in comparative genetics. His current areas of research focus on infectious diseases of cats and dogs in shelter a...
متن کاملFeline infectious peritonitis.
The article discusses feline infectious peritonitis (FIP), an important disease frequently seen in veterinary practice. FIP causes many problems to the veterinarian as it can be difficult to definitively diagnose the disease, as there is no effective treatment, and as prophylactic interventions are not very successful. Although intense research has created a lot of new knowledge about this dise...
متن کاملFeline infectious peritonitis.
Feline infectious peritonitis (FIP) frequently results in death in cats. It is caused by a mutated, highly contagious coronavirus, and it is more common in indoor cats in multicat households. A complex interaction between the coronavirus and the feline immune system causes disseminated vasculitis, which is the hallmark of FIP. New tests are being developed, but the antemortem diagnosis of FIP c...
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ژورنال
عنوان ژورنال: Archives of Virology
سال: 2015
ISSN: 0304-8608,1432-8798
DOI: 10.1007/s00705-015-2370-x